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Adult Psychiatric Morbidity Survey 2023/4

• 2022-2025, funded by NHS Digital/Department of Health and Social Care
• The Adult Psychiatric Morbidity Survey (APMS) series provides data on the prevalence of both treated and untreated psychiatric disorder in the English adult population (aged 16 and over).
• Lead: Professor Terry Brugha
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Identification, recording, and reasonable adjustments for people with a learning disability and autistic people in NHS electronic clinical record systems: studies using routine data, data linkage and machine learning to improve access to, and quality of, NHS care

• 2025-2028, funded by the National Institute for Health & Social Care
• This project examines how well learning disability and autism is recorded in different electronic health records in the NHS, analysing big data to develop models to better identify patients and suggest adjustments to their care.
• Lead: Dr Rory Sheehan, Professor Andre Strydom (Kings College London); Co-Investigator Dr Samuel Tromans

The Content Study: A Mixed Methods Study to Evaluate the Implementation and Impact of the Oliver McGowan Mandatory Training on Learning Disability and Autism

• 2024-2027, funded by the National Institute for Health & Social Care
• This project evaluates the Oliver McGowan Mandatory Training on Learning Disability and Autism, which aims to improve the skills and knowledge of health and social care professionals in supporting people with these conditions, to determine how the OMMT is being delivered, how it impacts different professional and patient groups, and its association with clinical outcomes.
• Lead: Dr Samuel Tromans, Professor Terry Brugha, Co-Investigators Dr Jennifer Creese, Professor Nicola Mackintosh

Improving kidney failure risk calculations in ethnically diverse populations

• 2024-2025, funded by the National Institute for Health & Social Care
• This project evaluates the performance of Kidney Failure Risk Equation (KFRE) in ethnically diverse populations, to improve equality in predicting progression of renal disease.
• Lead: Dr Mariam Molokhia, Professor Dorothea Nitsch (Kings College London); Co-Investigator Dr Rupert Major
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RESPOND: Rescue for emergency surgery patients observed to undergo acute deterioration 

• 2023-2025, funded by the National Institute for Health & Social Care Research
• The RESPOND project aims to analyse how surgical teams currently treat deteriorating patients after routine abdominal surgery, and help them develop and test better response systems.
• Lead: Professor Peter McCullough (Oxford University Hospitals NHS Foundation Trust), Co-Investigator Professor Nicola Mackintosh

PremPath: Improving the optimisation and stabilisation of the preterm infant 

• 2023-2025, funded by the National Institute for Health & Social Care Research
• The PremPath project aims to look at how a pathway of care for babies who are born premature (before 37 weeks of pregnancy) in England is working in practice, and how best to improve it.
• Lead: Professor Nicola Mackintosh

Evaluating cross-regional implementation of interventions to reduce the burden of multiple long-term conditions

• 2022-2024, funded by the National Institute for Health & Social Care Research through the Advanced Research Collaboration East Midlands
• This project will undertake comparative, cross-case analysis to generate higher-level learning from across four different clinical initiatives about the challenges and facilitators of large-scale implementation in the context of multiple long-term conditions
• Lead: Professor Carolyn Tarrant

Workforce wellbeing implementation processes

• 2024-2026, funded by the National Institute for Health & Social Care Research through the Advanced Research Collaboration East Midlands
• This project aims to understand how individuals tasked with implementing workforce wellbeing interventions in healthcare settings prioritise interventions and the barriers and enablers to the successful implementation of interventions.
• Lead: Dr Jennifer Creese

Comparative efficacy and safety of antihypertensive strategies for diabetic kidney disease: a systematic review and component network meta-analysis 

• 2025-2026, funded by the National Institute for Health & Social Care Research
• This project aims to establish best practice standards for blood pressure lowering therapies in adults with diabetes who have or are at risk of kidney disease to identify those most efficacious in improving survival and reducing the risk of end-stage kidney disease.
• Lead: Dr Daniel March (Department of Cardiovascular Sciences), Co-Investigator Dr Rupert Major

Getting the bloods to the laboratory: developing interventions to improve the blood culture pathway for patient safety and antimicrobial stewardship 

• 2024-2026, funded by the National Institute for Health & Social Care Research
• This project aims to create a bundle of interventions to optimise practices from the point of blood sampling through to transport of samples to the laboratory, by identifying situational factors that affect blood sampling for acute patients prescribed broad-spectrum antibiotics.
• Lead: Professor Carolyn Tarrant

MOMENTS: Enabling safety culture development practices across maternity and neonatal services 

• 2021- funded by NHS England/NHS Improvement
• This ongoing programme of work explored ‘safety culture-as-practiced’ in maternity care, and developed a set of resources for care teams to explore and enrich their own local safety culture. It is currently being integrated into the national Maternity and Neonatal improvement programme, with ongoing work to explore the transferability of MOMENTS to other settings.
• Lead: Professor Nicola Mackintosh

GM-PSRC: Greater Manchester Patient Safety Research Collaboration 

• 2023-2028, funded by the National Institute for Health & Social Care Research
• The National Institute for Health and Care Research Greater Manchester Patient Safety Research Collaboration (NIHR GM PSRC) aims to make health and care systems safer, especially for individuals, families, and communities with the greatest need for improvement. One of 4 interconnected themes, Enhancing Cultures of Safety (ECoS) is led by the University of Leicester. 
• Lead: Professor Darren Ashcroft (University of Manchester); ECoS theme leads Professor Natalie Armstrong (City St George’s University London), Professor Carolyn Tarrant, Professor Nicola Mackintosh

The Patient Safety Specialist role: a formative evaluation

• 2025-2028, funded by the Health Foundation and THIS Institute
• This project aims to build a detailed understanding of the Patient Safety Specialist role and its implementation in the NHS, and explore challenges and opportunities associated with delivering improvement through this role.
• Lead: Professor Graham Martin (University of Cambridge), Co-Investigator Dr M Farhad Peerally

SCALE-ENDO: Study of communication and adaptive capacity using in-situ learning Environments based on real life risks in endoscopy 

• 2024-26, funded by the Medical Protection Society Foundation
• The SCALE-ENDO project aims to improve safety in gastrointestinal endoscopy by developing and evaluating team-based in-situ simulations, grounded in real-world risks in endoscopy settings as identified through a mixed-methods analysis
• Lead: Dr M Farhad Peerally
• More information